For this reason, these drugs are contraindicated in patients with bilateral renal artery stenosis or patients with heart failure who have hypotension. Unintentional paediatric ingestions of angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists. Consider every hour dosing in patients who experience diminished blood pressure response towards the end of a hour dosing interval. RAAS system blockade can take place at several levels. Author Information Authors Robert D. Newborn infants are at a theoretical risk of hypotension due to ARB as these drugs may end up in the breast milk. To access free multiple choice questions on this topic, click here. Review [Direct renin inhibitor aliskiren in the treatment of cardiovascular and renal diseases]. Similar articles in PubMed.
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