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Mayo Clinic, Rochester, Minn. Occasionally, ambiguous genitalia may be suspected before birth prenatally. The mother's egg contains an X chromosome, and the father's sperm contains either an X or a Y chromosome. Show references What is ambiguous uncertain genitalia? Possible risk factors for ambiguous genitalia include a family history of:. Whether this tissue becomes male organs or female organs depends on the chromosomes and the presence or absence of male hormones. Mayo Clinic Marketplace Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.

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